Research theme :
Developing a new strategy for how novel biomaterials affect single stem cell behavior
Developing hydrogels with advanced functionalities for tissue regeneration

＜Specialties＞
Polymeric biomaterial, Hydrogel, Stimuli-responsive, Self-healing material, Single-cell encapsulation, Cell mechanotransduction

iksung_cho'@'ms.ifoc.kyushu-u.ac.jp

1. I.S. Cho, P. Gupta, N. Mostafazadeh, S.W Wong, S. Saichellappa, S. Lenzini, Z. Peng, J.W. Shin, Deterministic Single Cell Encapsulation in Asymmetric Microenvironments to Direct Cell Polarity, Advanced Science, 10(3), 2206014 (2022)
   DOI : https://doi.org/10.1002/advs.202206014
2. S.W. Wong, C. Tamatam+, I.S. Cho+, P.T. Toth, R. Bargi, P. Belvitch, J.C. Lee, J. Rehman, S.P. Reddy, J.W. Shin, “Inhibition of aberrant tissue remodeling by mesenchymal stromal cells singly coated with soft gels presenting defined chemomechanical cues, Nature Biomedical Engineering, 6(1), 54-66 (2021).
   DOI : https://doi.org/10.1038/s41551-021-00740-x
3. I.S. Cho, T. Ooya, “Cell‐Encapsulating Hydrogel Puzzle: Polyrotaxane‐Based Self‐Healing Hydrogels” Chemistry-A European Journal, 26(4), 913-920 (2020)
   DOI : https://doi.org/10.1002/chem.201904446
4. I.S. Cho, H.M. Oh, M.O. Cho, B.S Jang, J.K. Cho, K.H. Park, S. W. Kang, K.M. Huh, “Synthesis and characterization of thiolated hexanoyl glycol chitosan as a mucoadhesive thermogelling polymer”, Biomaterials research, 22(30), 1-10  (2018)
   DOI : https://doi.org/10.1186/s40824-018-0137-7
5. I.S. Cho, C.G. Park, B.K. Huh, M.O. Cho, Z. Khatun, Z. Li, S.W. Kang, Y.B. Choy, K.M. Huh, “A thermos-sensitive hexanoyl glycol chitosan-based ocular delivery system for glaucoma therapy”, Acta biomaterialia, 39, 124-132 (2016)
   DOI : https://doi.org/10.1016/j.actbio.2016.05.011